Dr R Lalthangliana is the Mizo National Front (MNF) leader and the present Health and Family Welfare, Higher and Technical Education, Commerce and Industry Minister in the Zoramthanga Cabinet. In the 2018 Mizoram Assembly Election, Lalthangliana won the South Tuipui constituency by defeating Congress candidate John Siamkunga with a margin of 1,469 votes. He won his first Assembly election from Lunglei North in 1989 by just 183 votes. He retained his seat in 1993, 1998 and 2003. He won Lunglei West in 2008 but lost it in 2013 when he was defeated by Congress candidate Chalrosanga Ralte. He is again contesting the upcoming Mizoram Assembly Election 2023 against C Laldintluanga of Congress and Zoram People's Movement's (ZPM) Jeje Lalpekhlua Fanai.