Four-time champion Italy failed to qualify for the 2018 World Cup, missing the tournament for the first time since 1958 after losing in the playoffs to Sweden.
Mitrovic's 90th-minute header left Cristiano Ronaldo and Portugal stunned in a 2-1 win for Serbia in Lisbon, which gave Serbia an automatic qualifying spot at the World Cup in Qatar.
Cristiano Ronaldo’s chance to play at possibly his last World Cup could hinge on the result of Portugal's winner-take-all clash against Serbia.
Ronaldo extended his men's record tally of international goals to 115 by scoring the 58th hat trick of his career for club and country in Portugal's 5-0 win over Luxembourg.
In his European record 181st game for Portugal — breaking a tie with his former Real Madrid teammate Sergio Ramos’s mark for Spain — Ronaldo score his 112th goal to stretch his men’s world record.
Ronaldo made his most decisive intervention with virtually the last kick of the game at Old Trafford to complete United's dramatic comeback in a 2-1 victory over Villarreal.
The club captain was sent on by manager David Moyes to take the penalty after Luke Shaw handled in the area.
On Saturday, Ronaldo marked his return to United, scoring twice in United's 4-1 victory over Newcastle in the Premier League tie.
The Bianconeri remained winless in Serie A and slumped to their second consecutive defeat since Ronaldo went back to Manchester United after losing at Napoli 2-1 on Saturday.
There was a tap-in from Ronaldo in the first half and a low strike after the break to restore the lead after Javier Manquillo equalized.
The five-time world player of the year was a part of Manchester United from 2003-09, where he netted 118 goals in 292 games.
On August 27, United had signed Ronaldo on a two-year contract with an obligation to extend for a further year.
Manchester United vs Newcastle United Live Streaming Premier League: Find full details on when and where to watch Man Utd vs Newcastle Live. You can watch MUFC vs NUFC Live Online on Hotstar and TV Telecast on Star Sports Select.
Solskjaer said Ronaldo is ready to feature having had a preseason with Juventus and also having played the full game for Portugal in a World Cup qualifier against Ireland last week.
Ronaldo, who broke the internet with his return to the English club after 12 long years, is expected to make his debut against Newcastle United
One of the best players in the history of soccer is making an emotional return for a second spell at one of the world’s biggest teams, so it’s understandable that Ronaldo has been the talk of the town.
Bernardo Silva, André Silva and Diogo Jota scored a goal each for visiting Portugal, who moved three points ahead of Serbia in Group A.
Ronaldo scored twice in the final minutes of the match to set up a 2-1 win for Portugal.
Cristiano Ronaldo scored in the 89th minute to equalise for Portugal, and then scored a winner six minutes into stoppage time to break Irish hearts.
Man United manager Ole Gunnar Solskjaer will have to deal with extra pressure following a transfer window that couldn't have gone much better.
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