Real Madrid at virtually full strength against Espanyol

Meanwhile, Isco could also start in an advanced midfield role after Ancelotti said as much in his conference, hinting that he could give a rest to striker Karim Benzema.

The Espanyol-Real Madrid tie is the first of the four quarter- final clashes and Wednesday will see two more as Barcelona return to play Levante after their 1-1 draw in the Ciudad de Valencia Stadium in the league Sunday evening.