New York, Sept 7 : India's Leander Paes alongwith his partner Radek Stepanek lost the UP Open men's doubles final 3-6, 4-6 to the Bryan brothers of the US on Friday night.
Bob and Mike Bryan collected a record-equalling 12th Grand Slam men's doubles title.
The second-seeded American brothers went level with Australia's John Newcombe and Tony Roche as the most successful partnership of all time.
Friday's win was their fourth at the US Open, following triumphs in 2005, 2008 and 2010.
They also won the 2003 French Open, the 2006, 2007, 2009, 2010 and 2011 Australian Open titles as well as Wimbledon in 2006 and 2011, a record that also means they are the most successful in the Open era.
India's Paes and Czech partner Stepanek had defeated the American duo in the Australian Open final earlier this year.