The 22-year-old was suffering from an irreversible brain damage since last seven months. She was found face down and unresponsive in her bath tub in her Atlanta, Georgia home on January 31.
She was the only daughter of pop legend Whitney Houston and singer Bobby Brown.
On Sunday, she died at a hospice in Duluth, Georgia.
As per a statement cited by US media, the Houston family had said, “She is finally at peace in the arms of God”.
They had also added, “We want to again thank everyone for their tremendous amount of love and support during these last few months”.
As per a leading daily, the young girl's accident linked to an apparent drug overdose - drew eerie parallels with the death of her mother, who was found face down in a bathtub in a Los Angeles hotel on February 11, 2012, on the eve of the Grammy Awards.