Saina said, "It is definitely a tough year. Throughout there were so many big tournaments and we did not even have time to rest and think about the next event."
It was heartbreak for Saina, who couldn't put enough pressure on Han, a 2017 world junior championship silver medallist, losing 18-21, 8-21 in a 34-minute final.
Second-seeded Saina, prevailed over Indonesian Ruselli Hartawan 12-21, 21-7, 21-6 to set up a clash with China's Han Yue.
Saina will next face eighth-seeded compatriot, Rituparna Das, while Kashyap will take on Thailand's Sitthikom Thammasin in quarterfinals.
In Sindhu's absence, Saina will be the cynosure of all eyes and the celebrated Indian has been in decent form this year having won a gold at the Commonwealth Games and a bronze at the Asian Games.
Saina looked in good touch initially but couldn't match the pace of Tzu Ying, later on, to squander four-game points and lose the opening game.
Praneeth was no match for Asian Games champion Jonatan Christie of Indonesia, going down 16-21, 14-21 in a men's singles match.
Srikanth showed great determination to outwit Korea's world No 25 Lee Dong Keun 12-21, 21-16, 21-18 in a second-round clash that clocked an hour and 13 minutes.
Sindhu, who is currently competing at the French Open in Paris, jumped one spot to stay one spot behind Chinese Taipei's Tai Tzu Ying, who continues to dominate the rankings.
World No. 10 Saina will face either 2017 world champion Nozomi Okuhara of Japan or Spain's Beatriz Corrales next. Fifth-seeded Srikanth will meet Korean Lee Dong Keun.
Shraddha Kapoor recently said that the ace badminton player's journey mirrors her own.
In an exciting but energy-sapping 52-minute final, Saina lost 13-21 21-13 6-21 to the superior Chinese Taipei rival.
Saina Nehwal got the better of Gregoria Mariska Tunjunng of Indonesia 21-11 21-12 in a lop-sided affair which lasted 49 minutes.
In the women's doubles, Ashwini Ponnappa and N Sikki Reddy's spirited campaign came to an end.
This was Nehwal's second career win over Yamaguchi, who has won six times in the head-to-head encounters between the two.
Third seed Sindhu lost 17-21 21-16 18-21 to Zhang in a hard-fought opening encounter that lasted 56 minutes.
Top shuttlers including Olympic medallists PV Sindhu, Saina Nehwal, world champion Carolina Marin and former world no 1 Victor Axelsen will headline the players' auction.
Shraddha Kapoor had begun training under the guidance of former badminton player Pullela Gopichand.
Bollywood Latest News, Shraddha Kapoor is essaying the role of Indian badminton player Saina Nehwal in her biopic. On Saturday, she shared the first look from the movie.
The fifth-seeded Indian squandered four match points to go down 21-15, 15-21, 20-22 to the third-seeded Okuhara in a match that lasted almost an hour.
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