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Simple home test with just a paper strip could predict cancer and malaria in coming years, says study

Washington DC: Testing yourself for cancer or malaria could be as simple as testing your blood sugar or taking a home pregnancy test in coming years, according to a recent study. Chemists at the Ohio

India TV Lifestyle Desk India TV Lifestyle Desk Published on: June 30, 2016 11:29 IST
Paper strip
Paper strip

Washington DC: Testing yourself for cancer or malaria could be as simple as testing your blood sugar or taking a home pregnancy test in coming years, according to a recent study.

Chemists at the Ohio State University are working on  developing paper strips that detect diseases including cancer and malaria. The cost of each strip will be around 50 cents.

Just a strip and a drop of blood is all what is required by anyone to get medically tested. The strip then could be sent to a laboratory on a regular basis and a person would only have to see a doctor only if the test comes out positive. 

The researchers, led by Abraham Badu-Tawiah explained that this idea and found that the tests were accurate even a month after the blood sample was taken, proving they could work for people living in remote areas.

Dr Badu-Tawiah brought this test so that people in rural Africa and southeast Asia could get cheap malaria diagnoses as in these palces the disease kills hundreds of thousands of people and infects hundreds of millions every year.

The researchers found that the test can be performed to detect any disease for which the human body produces antibodies, including ovarian cancer and cancer of the large intestine. 

The patent-pending technology could bring disease diagnosis to people who need it most--those who don't have regular access to a doctor or can't afford regular in-person visits, Badu-Tawiah said. "We want to empower people. 

If you care at all about your health and you have reason to worry about a condition, then you don't want to wait until you get sick to go to the hospital. You could test yourself as often as you want," he said.

This technology resembles today's "lab on a chip" diagnostics, but instead of plastic, the "chip" is made from sheets of plain white paper stuck together with two-sided adhesive tape and run through a typical ink jet printer.

Instead of regular ink, however, the researchers use wax ink to trace the outline of channels and reservoirs on the paper. The wax penetrates the paper and forms a waterproof barrier to capture the blood sample and keep it between layers. 

One 8.5-by-11-inch sheet of paper can hold dozens of individual tests that can then be cut apart into strips, each a little larger than a postage stamp. 

"To get tested, all a person would have to do is put a drop of blood on the paper strip, fold it in half, put it in an envelope and mail it," Badu-Tawiah said.

The technology works differently then paper-based medical diagnostics like home pregnancy tests, which are coated with enzymes or gold nanoparticles to make the paper change color. 

Instead, the paper contains small synthetic chemical probes that carry a positive charge. It's these "ionic" probes that allow ultra-sensitive detection by a handheld mass spectrometer. 

As per reports, badu-Tawiah hopes that they will be able to test the strips in a clinical setting within three years and till then they all are working to make the tests more sensitive.

They want people to use these strips non-invasively, with saliva or urine as the test material instead of blood.

The study appears in the Journal of the American Chemical Society.

(With Agency input)

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