Sri Lanka's Akila Dananjaya dismissed Evin Lewis, Chris Gayle and Nicholas Pooran off consecutive deliveries, before being hit for six sixes in an over by Kieron Pollard.
Evin Lewis scored a century as West Indies cruised to a five-wicket win over Ireland, securing a 3-0 whitewash.
Evin Lewis missed his century by a run as he guided West Indies to a five-wicket victory in the first ODI against Ireland in Barbados.
Evin Lewis suffered from an injury during fielding and had to be stretchered off during the third T20I between India and West Indies.
While Carlos Brathwaite will continue to lead the side, stand-in ODI captain Rovman Powell will serve as his deputy in the series.
Lewis' withdrawal comes as a major setback for the Windies as they have already named a squad without their stars such as Chris Gayle and Andre Russel.
Mumbai suffered dying-moment defeats in the three games played so far - against Chennai Super Kings, Sunrisers Hyderabad and Delhi Daredevils.
Evin Lewis became the 500th player to debut in the Indian Premier League (IPL) though he was dismissed for duck in the IPL 2018 opening match.
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