The Indian duo opened up a 7-4 lead early on but they lacked the angles in their attack as their opponents managed to enter the break with an 11-9 lead after Satwik faltered with his return.
Satwiksairaj Rankireddy and Chirag Shetty entered the quarterfinals of the China Open, but disappointment continued in the singles.
Parupalli Kashyap lost 13-21, 19-21 to seventh seed Victor Axelson in a match that lasted 43 minutes at the Haixia Olympics Sports Center to crash out of the China Open.
Saina Nehwal lost 9-21 12-21 in the women's singles clash that lasted just 24 minutes to make an early exit from the China Open.
Osaka bounced back from a set down to top-seeded Ash Barty, cruising through the final two sets to defeat the top-seeded Australian 3-6, 6-3, 6-2 and accomplish her goal of returning to winning form on the tour's Asian leg.
Andy Murray's impressive run in the China Open came to an end in the quarterfinals, but Naomi Osaka and Ashleigh Barty proceeded to the semis in the women's singles.
In the men's draw, world number 19 John Isner fired off 21 on his way to a hard-fought 7-6 (3), 7-5 win over British qualifier Daniel Evans in just under two hours.
World No. 3 Elina Svitolina was made to sweat but avenged her loss in Miami this year against China's Wang Yafan, needing two tie-breaks to move into the round of 16 with a straight-sets 7-6 (5), 7-6 (1) victory
Two-time Grand Slam champion Simona Halep has confirmed her participation in the upcoming China Open.
Carolina Marin defeated Tai Tzu Ying 14-21, 21-17, 21-18 to lift the China Open.
Almost a month after dispatching the Indonesian en route his historic world championships bronze at Basel, world no.15 Praneeth went down to the same opponent 21-16, 6-21, 16-21 in 55 minutes to end his campaign.
Satwik and Chirag, ranked 15th in the world, ran out of steam after a decent start against their fourth-seeded opponents and went down 19-21 8-21 in the second-round match.
PV Sindhu beat China's Xuerui Li 21-18, 21-12 in the first round of the China Open World Tour Super 1000.
Saina Nehwal was defeated 10-21, 17-21 by Thailand's Busanan Ongbamrungphan in the first round of China Open.
The Indian duo of Satwiksairaj Rankireddy and Ashwini Ponnappa registered a stunning win over World No.7 Indonesia's Praveen Jordan and Melati Daeva.
The Indian pair defeated the sixth-seeded pair 22-20, 17-21, 21-17 in a thrilling opening round clash that lasted for 50 minutes at the Olympic Sports Center Xincheng Gymnasium.
PV Sindhu, who became India's first badminton World Champion, will return to action in the China Open on Tuesday.
Indian shuttler HS Prannoy was forced to pull out of the two tournaments with dengue.
Wozniacki said eight was her lucky number and, having won in Beijing eight years ago, she "felt it was my year."
Halep lost the first set 6-1 to Tunisia's Ons Jabeur before retiring with a back injury that she also had problems with at last week's Wuhan Open.
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