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Planning to get smoke free? First three months post quitting are most crucial, claims study

After you quit smoking, a chemical released by neurons which sends signals to other nerve cells, return to normal levels only after three months, claims a new study. According to a study published recently in

India TV Lifestyle Desk, New York [ Published on: July 31, 2016 17:26 IST ]
Representative Image
Representative Image

After you quit smoking, a chemical released by neurons which sends signals to other nerve cells, return to normal levels only after three months, claims a new study.

According to a study published recently in the journal Biological Psychiatry, the normalisation of dopamine systems suggested smoking-related deficits is a consequence of chronic smoking.

The study also suggested that the first three months after one stops smoking may be a particularly vulnerable time for relapse.

These findings by a team of researchers from Germany raise the possibility that treatments might be developed that normalise the dopamine system in smokers.

A major challenge in understanding substance-related disorders lies in uncovering why only some individuals become addicted, according to study lead author Lena Rademacher from the University of Lubeck.

To answer this question, Rademacher's team examined dopamine function in chronic smokers before and after long-term cessation. 

The researchers used a brain imaging technique called positron emission tomography to measure an index of the capacity for dopamine production in 30 men who were nicotine-dependent smokers and 15 non-smokers. 

The initial scan revealed a 15-20 per cent reduction in the capacity for dopamine production in smokers compared with non-smokers.

The researchers expected this impairment to persist even after quitting, which would suggest it could be a marker of vulnerability for nicotine addiction. 

"Surprisingly, the alterations in dopamine synthesis capacity normalised through abstinence," Rademacher said.

The study suggests that the first three months after one stops smoking may be a particularly vulnerable time for relapse, in part, because of persisting dopamine deficits. This observation raises the possibility that one might target these deficits with new treatments.

(With Agency input)

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