The 30-share index, which gained 140 points in the past three sessions, fell by 51.70 points, or 0.29 per cent, to 17,486.97 with stocks of IT, metal and realty sectors leading the fall.
Similarly, the wide-based National Stock Exchange index Nifty declined by 15.45 points, or 0.29 per cent, to 5,311.85.
Brokers said besides profit-booking by speculators after recent gains and a weak trend on Asian bourses followed by a overnight losses at the US market as central banks' moves in China and Europe to boost growth failed to impress investors, influenced the sentiment here.
In Asian region, Hong Kong's Hang Seng index declined by 0.28 per cent, while Japan's Nikkei Index was down by 0.36 per cent in the morning trade today.
The US Dow Jones Industrial Average ended 0.36 per cent lower in yesterday's trade.