Daniil Medvedev went past Stan Wawrinka 7-6, 6-3, 3-6, 6-1 on Tuesday despite 12 double-faults and a body that's just short of breaking down.
Novak Djokovic was trailing Stan Wawrinka 4-6, 5-7, 1-2 when he decided to call it quits.
Novak Djokovic earned a 6-3, 6-4, 6-2 victory over Denis Kudla in the third round of the US Open on Friday.
In his first trip to Roland Garros since 2015, Federer would be wrapping up a 7-6 (4), 4-6, 7-6 (5), 6-4 victory over Wawrinka, his friend and Swiss Olympic and Davis Cup teammate, to make his way to the semifinals.
Stan Wawrinka outlasted Greece's Stefanos Tsitsipas 7-6 (8-6), 5-7, 6-4, 3-6, 8-6 in a marathon French Open fourth-round clash that lasted five hours and nine minutes.
The unseeded Wawrinka beat top-seeded Kei Nishikori 6-2, 4-6, 6-4 in the ABN AMRO World Tournament semifinals to face Gael Monfils for the title on Sunday.
Novak Djokovic, Alexander Zverev, Stan Wawrinka, Milos Raonic and Kei Nishikori were all off to winning starts in the first round of Australian Open.
Murray hadn't played in a Grand Slam tournament since Wimbledon last year, before needing hip surgery that has limited him to just eight matches this year.
Returning to the place where he claimed the second of his three Grand Slam titles did not help Wawrinka shake off his poor form.
Wawrinka was swept aside by Marton Fucsovics of Hungary 6-4, 6-0 in the quarterfinals for his first defeat in front of home fans at Geneva since 2015.
It was the first win in an ATP tournament for the 21-year-old Dutchman, who dominated the second and third sets against a lacklustre Wawrinka.
Federer will next face Frenchman Richard Gasquet in the round of 32 on Saturday.
Stan Wawrinka never looked capable of winning his third-round match, losing 6-2, 6-1, 6-4 to American Tennys Sandgren.
Wawrinka is also looking for a new coach to work alongside Yannick Fattebert after Magnus Norman decided to retire in October.
Earlier, Djokovic was expected to make a return in 2018, but the former world number one has decided to start his season early at the Mubadala World Tennis Championship, beginning in Abu Dhabi on December 28.
The Chennai Open will now be held in Pune next year and would be henceforth called "Maharashtra Open".
Stan Wawrinka - No.3 ranked iced his knee during changeovers and never was able to summon his best tennis at the Centre Court of All England Club.
A brief look at some of the players who are capable of breaking their dominance of Big 4 in Tennis at the All England Club.
Rafael Nadal won his record 10th French Open title, beating No.3 Stan Wawrinka in straight sets.
'Stan the Man' defeated world number one Andy Murray in a grueling five-setter to set a date against 'King of Clay' Rafael Nadal in the final of men's singles at French Open 2017.
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