Donald Trump Jr. and his wife, Vanessa Trump, say in a joint statement issued after an uncontested New York divorce filing they've decided to go their separate ways.
The couple said on Thursday they "will always have tremendous respect for each other" and their families.
The Trumps are both 40 years old and were married in 2005. They say their five children will remain their top priority.
The statement came hours after Vanessa Trump filed for divorce in state Supreme Court in Manhattan.
The 2007 birth of the couple's first child made Donald Trump Sr. a grandfather a decade before he became president.
The divorce announcement comes as Trump Jr. remains a focus of the special counsel's investigation into Trump ties to Russia.