Paris Saint-Germain stars Neymar and Kylian Mbappe picked up injuries during their respective international friendlies on Tuesday.
Mbappe was forced off the pitch with an apparent shoulder injury during the world champion's friendly game against Uruguay.
The PSG star had to be substituted after he fell awkwardly on his right shoulder near the half-hour mark at the Stade de France with the match scoreless.
Mbappe jumped to avoid contact with goalkeeper Martin Campana and went down in pain, forcing coach Didier Deschamps to substitute him for Marseille forward Florian Thauvin.
He is the second Paris Saint-Germain star to be injured during Tuesday's games, with Brazil's Neymar also coming off with an apparent groin problem during his team's friendly against Cameroon.
Neymar was substituted with an apparent groin injury during the first half of Brazil's friendly against Cameroon.
The Brazilian star was taken off after just eight minutes and was replaced by Everton's Richarlison, who gave his team a 1-0 win with a header just before the halftime break.
Neymar was apparently injured after missing a shot five minutes into the game. He tried to stay on but was soon forced to come off.
The injury will be a concern for his club Paris Saint-Germain, which faces a key Champions League match against Liverpool next week and also saw France star Kylian Mbappe pick up a shoulder problem in another friendly game on Tuesday.
In a quick interview with TV Globo, Brazil's team doctor Rodrigo Lasmar said it was too early to determine the extent of the injury.
"He is feeling discomfort in his groin," Lasmar said.