Seamer Mohammad Abbas grabbed a match haul of 10/95 as Pakistan recorded an emphatic 373-run victory over Australia in the second Test to clinch the series 1-0 on Friday.
Australia was bowled out for 164 after lunch on the fourth day after given an improbable winning target of 538.
2nd Test, Day 3: Babar Azam misses ton but Australia need to survive two days to avoid defeat in Abu Dhabi
Abbas became the first fast bowler to take 10-for in the 16-year history of cricket Tests in the United Arab Emirates. His 17 wickets in the series earned man of the series.
Usman Khawaja, whose herculean century helped Australia salvage a draw in the thrilling first Test, couldn't bat in the second innings after tearing a left knee cartilage in the warmup on Thursday.
Australia sorely missed Khawaja-like grit from any of its batsmen on Friday.
Abbas, defying the slow turning pitch, again jolted the top order with four quick wickets in the first hour on day four. The right-arm seamer then had top scorer Marnus Labuschagne caught behind for 43 after lunch to finish with 5/62 to go along with his first innings effort of 5/33.
Legspinner Yasir Shah ran through the tailenders with 3/45, finishing off the match by having Jon Holland caught in the slips on 3.
"We weren't up to the challenge with the bat," Australia captain Tim Paine said. "There's certainly no sugar coating that we've got some real issues with our batting."
Needing to hold out for more than two days for another draw, Australia began the day on 47/1.
Travis Head (36) and Aaron Finch (31) stretched their second-wicket stand to 61 runs before Abbas struck four blows in a high-class exhibition of seam and swing bowling.
Head edged to substitute wicketkeeper Mohammad Rizwan, standing in for captain Sarfraz Ahmed, who went to hospital for precautionary scans when he woke up on Friday and complained of headaches.
"I'm feeling fine, just wanted to see if there was concussion," Ahmed said.
Abbas then had Mitchell Marsh lbw on 5 when Pakistan successfully went for a video referral against umpire Richard Illingworth's not out decision.
Pakistan stand-in captain Asad Shafiq outsmarted Finch's tactic of standing well outside his crease while facing Abbas, by making Rizwan stand close to the stumps, forcing the batsman inside the crease. The switch paid off as Abbas trapped Finch lbw.
Two balls later, Paine was out without scoring while trying to leave a ball that nipped back enough and knocked over the off stump.
"Mohammad Abbas challenged our defence time and time again," Paine said.
Shah then had Mitchell Starc (28) and Peter Siddle (3) both leg before wicket. Siddle could have survived but chose not to go for a video referral as the replays suggested the ball pitched outside leg stump.
Labuschagne shared the best partnership of the innings by adding 67 runs with Starc for the sixth wicket before Abbas returned after lunch and had him caught behind off a short-pitched delivery.
Paine rued letting Pakistan slip away from 5/57 on day one. Fakhar Zaman, on debut, and Ahmed hit 94s, then Abbas, playing his 10th Test, tore through the Australians.
"The way Abbas has bowled in the series, it is one of the biggest positives for us," Ahmed said.
"Fakhar has had an excellent debut, he's an important player."
They head into a three-match T20I series starting next Wednesday.
(With AP Inputs)